- Solution stability studies (define sensitivities to pH, buffer, buffer strength, and salt concentration)
- Solubility curves (determine ionization constant (pKa), define osolvent and complexing solubility)
- Agglomeration or micelle determination and size
- Forced degradation and compound/protein stabilization studies
- Determine compound or protein sensitivity to pH, heat or oxidation
- Stabilizer screening (using pharmaceutical, veterinary or agricultural approved additives)
- Prototype formulas developed based on preformulation study results
- Optimize formulas and monitor on stability to pick the champion